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OTA was found to chelate ferric ions (Fe 3 ), facilitating their reduction to ferrous ions (Fe 2 ), which in the presence of oxygen, provided the active species initiating LPO [74]

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Cyclooxygenase induction is essential for NGF synthesis enhancement by NGF inducers in L-M cells

Dietary TMAO is subject to retro-conversion: i.e., it can undergo microbial reduction to TMA by Enterobacteriaceae followed by hepatic conversion back to TMAO 16